Hemodynamic impingement and the initiation of intracranial side-wall aneurysms
نویسندگان
چکیده
منابع مشابه
Endothelial Nitric Oxide Synthase and Superoxide Mediate Hemodynamic Initiation of Intracranial Aneurysms
BACKGROUND Hemodynamic insults at arterial bifurcations are believed to play a critical role in initiating intracranial aneurysms. Recent studies in a rabbit model indicate that aneurysmal damage initiates under specific wall shear stress conditions when smooth muscle cells (SMCs) become pro-inflammatory and produce matrix metalloproteinases (MMPs). The mechanisms leading to SMC activation and ...
متن کاملHemodynamic Differences in Intracranial Aneurysms before and after Rupture.
BACKGROUND AND PURPOSE Rupture risk of intracranial aneurysms may depend on hemodynamic characteristics. This has been assessed by comparing hemodynamic data of ruptured and unruptured aneurysms. However, aneurysm geometry may change before, during, or just after rupture; this difference causes potential changes in hemodynamics. We assessed changes in hemodynamics in a series of intracranial an...
متن کاملHemodynamic differences between unruptured and ruptured intracranial aneurysms during observation.
BACKGROUND AND PURPOSE We evaluated several hemodynamic parameters for the prediction of rupture in a data set of initially unruptured aneurysms, including aneurysms that ruptured during follow-up observation. METHODS Aneurysm geometry was extracted from CT angiographic images and analyzed using a mathematical formula for fluid flow under pulsatile blood flow conditions. Fifty side-wall inter...
متن کاملWall Mechanical Properties and Hemodynamics of Unruptured Intracranial Aneurysms.
BACKGROUND AND PURPOSE Aneurysm progression and rupture is thought to be governed by progressive degradation and weakening of the wall in response to abnormal hemodynamics. Our goal was to investigate the relationship between the intra-aneurysmal hemodynamic conditions and wall mechanical properties in human aneurysms. MATERIALS AND METHODS A total of 8 unruptured aneurysms were analyzed. Com...
متن کاملHemodynamic changes due to stent placement in bifurcating intracranial aneurysms.
OBJECT The aim of this study was to measure changes in intraaneurysm flow dynamics and mechanical stresses resulting from the placement of Neuroform stents in bifurcating intracranial aneurysm models. METHODS A digital particle image velocimetry (DPIV) system was used to measure the pulsatile velocity and shear stress fields within the aneurysm and at the aneurysm neck-parent artery interface...
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ژورنال
عنوان ژورنال: Interventional Neuroradiology
سال: 2018
ISSN: 1591-0199,2385-2011
DOI: 10.1177/1591019918754380